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10.1016/j.immuni.2013.10.022 34 FukuiS.MizunoM.TawadaM.SuzukiY.KojimaH.MatsukawaY.et al (2023)

Mitomycin c induces apoptosis in rheumatoid arthritis fibroblast-like synoviocytes via a mitochondrial-mediated pathway

However, concerns regarding gene dosage will have to be considered with gene therapy and modulation of frataxin expression since frataxin overexpression was reported to be toxic in several models (Navarro et al., 2011